WebDec 17, 2010 · Proliferating cell nuclear antigen (PCNA) is an evolutionarily well-conserved protein found in all eukaryotic species as well as in Archaea. PCNA was first shown to act as a processivity factor of DNA polymerase δ, which is required for DNA synthesis during replication (Tan et al., 1986; Bravo et al., 1987; Prelich et al., 1987). http://yuxiqbs.cqvip.com/Qikan/Article/Detail?id=6825539

Proliferating cell nuclear antigen definition and meaning Collins ...

WebAntigen KI-67, also known as Ki-67, Ki-67 or MKI67 (Marker Of Proliferation Ki-67), is a protein that in humans is encoded by the MKI67 gene (antigen identified by monoclonal … WebProliferating cell nuclear antigen (PCNA): a key factor in DNA replication and cell cycle regulation. Most plant PCNAs exhibit features similar to those found for PCNAs of other … epcr ychart

Vps4b基因敲除鼠上皮根鞘中细胞角蛋白14和增殖细胞核抗原的表 …

WebThyroid hormone (l-thyroxine, T 4, or 3,5,3′-triiodo-l-thyronine, T 3) treatment of human papillary and follicular thyroid cancer cell lines resulted in enhanced cell proliferation, measured by proliferating cell nuclear antigen (PCNA). Thyroid hormone also induced activation of the Ras/MAPK (ERK1/2) signal transduction pathway. WebProliferating Cell Nuclear Antigen (PCNA) is a highly conserved protein. PCNA is a cofactor of DNA polymerase ? in eukaryotic cells and helps to increase the processivity of leading strand synthesis during DNA replication. PCNA is an example of a DNA clamp as it encircles the DNA, (which, as a result, creates topological link to the genome). WebProliferating cell nuclear antigen (PCNA) is a protein with molecular weight of 36,000 that works as a DNA sliding clamp and functions well in regulating cell proliferation. [2] It was reported that the high expression level of PCNA or over-expression of p53 have a negative effect on tumor recurrence, tumor growth, and survival. drinking glasses from the 70s