Diselenolane-mediated cellular uptake
WebJan 17, 2024 · Europe PMC is an archive of life sciences journal literature. WebApr 14, 2024 · Autophagy is a highly conserved process that functions to transport cargos to the lysosome for recycling and cellular degradation in eukaryotes [].Autophagy not only serves to remove defective or damaged organelles and cellular components by self-digestion, as a catabolic mechanism, it recycles substrates required to sustain …
Diselenolane-mediated cellular uptake
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WebThis conclusion, resulting from the synthesis and evaluation of a series of COC–antibiotic conjugates, supports that COCs penetrate mammalian cells along nontrivial uptake pathways involving dynamic covalent exchange chemistry, mobility along disulfide tracks, and adaptive micellar pores. Citing Literature 21, Issue WebApr 13, 2024 · To study the cellular uptake mechanism of SCPN topological isomers, PALA SCPNs were fluorescently labeled with Alexa Fluor 647 (AF647), as discussed above. ... (less than 20% downregulation by MβCD), but on the clathrin-mediated pathways, as revealed by the ∼40% MFI downregulation upon the treatment of CPZ (chlorpromazine) …
WebDiselenolane-mediated cytosolic delivery is non-toxic (MTT assay), sensitive to temperature but insensitive to inhibitors of endocytosis (chlorpromazine, methyl-β … WebAug 6, 2024 · In obesity, chronic membrane-localization of CD36 free fatty acid (FFA) translocase, but not other FFA transporters, enhances FFA uptake and intracellular lipid …
WebThese targeting ligands enable nanoparticles to bindto cell-surface receptors and enter cells by receptor-mediated endocytosis (FIG 1). Recent work comparing non-targeted and … WebIn the MTT assay, all glyco‐CPDs were non‐toxic at concentrations as high as 2.5 μ m. Consistent with thiol‐mediated uptake, glycosylated CPDs remained dependent on …
WebJan 17, 2024 · Diselenolane-mediated cytosolic delivery is non-toxic (MTT assay), sensitive to temperature but insensitive to inhibitors of endocytosis (chlorpromazine, methyl-β …
WebSimple cyclic disulfides under high tension mediate the uptake of giant substrates, that is, liposomes and polymersomes with diameters of up to 400 nm, into HeLa Kyoto cells. To place them at the surface of the vesicles, the strained disulfides were attached to the head‐group of cationic amphiphiles. hartmann solution usesWebDiselenolane-mediated cytosolic delivery is non-toxic (MTT assay), sensitive to temperature but insensitive to inhibitors of endocytosis … punaseetripuuWebMar 15, 2024 · We show that diseleno lipoic acid (DiSeL) delivers a variety of relevant substrates. DiSeL-driven uptake of artificial metalloenzymes enables bioorthogonal … hartmann toiletryWebSimple cyclic disulfides under high tension mediate the uptake of giant substrates, that is, liposomes and polymersomes with diameters of up to 400 nm, into HeLa Kyoto cells. To place them at the... punasolujen kokojakauma yli 14Web摘要： Cystine/glutamate antiporter solute carrier family 7 member 11(SLC7A11;also known as xCT)plays a key role in antioxidant defense by mediating cystine uptake,promoting glutathione synthesis,and maintaining cell survival under oxidative stress conditions.Recent studies showed that,to prevent toxic buildup of highly insoluble cystine inside … punase kapsa hautisWebNational Center for Biotechnology Information punasikurisalaattiWebIn the case of diselenolane, the uptake of 77 was more than 2.5 times higher than for 74 after 1 h incubation, making 77 the best 5-member ring transporter identified so far. 3.2.4.2. Concentration and Time Dependences on Cellular Uptake . The final localization of the fluorescence in the cells was determined by CLSM. hartmann yonna