WebCyclophosphamide is an alkylating agent, and prevents cell division primarily by cross-linking DNA and RNA strands. It is considered to be cell cycle phase-nonspecific. … http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Hydroxyurea_monograph_1Oct2013.pdf
BC Cancer Protocol Summary for Neoadjuvant or Adjuvant …
Webwere reported in more than 1% of patients in the product monograph or pivotal trials, and/or determined to be clinically important. 12. When placebo-controlled trials are available, adverse events are included if the incidence is >5% higher in the treatment group. ORGAN SITE SIDE EFFECT . http://www.bccancer.bc.ca/drug-database-site/Drug%20Index/Gemcitabine_monograph.pdf hyde park gentrification
CYCLOPHOSPHAMIDE - World Health Organization
Webwere reported in more than 1% of patients in the product monograph or pivotal trials, and/or determined to be clinically important. 5,15. ORGAN SITE SIDE EFFECT . Clinically important side effects are in . bold, italics. blood and lymphatic system/ febrile neutropenia Webformulation is doxorubicin (refer also to doxorubicin monograph). PHARMACOKINETICS: Interpatient variability no information found Distribution confined mostly to the vascular fluid volume cross blood brain barrier? no6 volume of distribution 1.93 L/m2 (range 0.96-3.85 L/m2) plasma protein binding no information found5 active metabolite(s) WebBackground: Chemotherapy with cyclophosphamide, vincristine and dacarbazine (CVD) can be used for palliative treatment of malignant pheochromocytoma and … mason saw and lawnmower